Mikhail Blagosklonny is a scientist who studies cancer and aging. He is also the professor of oncology at the Rosewell Park Cancer Institute based in Buffalo, New York. Blagosklonny is known for his extensive research and study of aging. Due to his knowledge in this field, doctor Blagosklonny recommends a drug known as Rapamycin to be used to prevent aging and as a result, prolong the lifespan of a person.
Rapamycin popularly known as Sirolimus (market name of Rapamune) is a medicinal drug that has been in use for some time in preventing organ transplant rejection. Besides this critical use, Rapamycin can also be used for treating a rare lung infection.
The reasons why doctor Blagosklonny believes that Rapamycin is the perfect as a medicine is that:
- Its immunosuppressant properties
After a successful organ transplant, the body may try rejecting the new organ, hence the surgery might fail. For this reason, doctors for a long time have been using anti-rejection drugs such as calcineurin inhibitors, but unfortunately, they have adverse side effects on the kidneys of the patient. Here is where Rapamycin comes in. It has lower toxicity levels as compared to other immunosuppressive drugs.
- Used for treating patients suffering from hemolytic
Uremic syndrome – such patients, requires an immediate kidney transplant and there is no guarantee that the new kidney wouldn’t contract the same disease. In such cases, Rapamycin is used as an immunosuppressive drug because of its low toxicity.
- Can be used to treat patients with a rare disease known as Lymphangioleiomyomatosis (LMA)
Affects mostly, women.Rapamycin blocks the mTOR gateway that opens due to mutation of Tuberous Sclerosis Complex gene (TSC2).
- It is used to treat cancer.
Sirolimus has antiproliferative properties; hence can help the body fight tumors.
- Used for coating the coronary stents to prevent re-stenosis in the arteries from happening.
- Treatment of Tuberous Sclerosis Complex (TSC)
This congenital infection that can cause a growth of tumors in the brain, kidney, heart, as well as other organs.Rapamycin has been found to reduce the infection in kids and also in adults.
- Used for treating Facial angiofibromas
This is an infection that over 80 percent of TSC patients suffer from. It is a kind of rashes that attack the face of the patient. Rapamycin can be used in the form of gel, cream, or even ointments to solve this problem
- Increase the lifespan of a person, though still under research.
Doctor Blagosklonny has been in the forefront in research on the subject. So far there is no conclusive evidence that it can prolong the life of a person.
Another potential usage of the drug still under research is;
- Treatment of Alzheimer’s disorder
- Treatment of Muscular Dystrophy
- Treatment of Systemic Lupus Erythematosus (SLE)
Doctor Blagosklonny has been very instrumental in this research to finding treatment for various diseases that affect humans especially cancer and aging. He is trying to prove the fact that cancer is more common to people of certain age. He has been an inspiration to not only his fellow scientists but to students who are learning in the field.
Blagosklonny has a mission to uncover cheap and effective treatment to cancer. He is researching on best ways to remove cancerous cells from the body without affecting healthy body cells.